Sucralose was approved in Canada in 1991 and then in 1998 in the U.S., where it was sold under the name «Splend». Prior to that sucralose in 13 years took more than a hundred of toxicity tests, which revealed no carcinogenic or adverse effects on reproductive function, nervous system, or genetics. 

Sponsored by producing studies have identified the approximate daily intake of sucralose at a level of 1.1 mg per kilogram of body weight. Optimal reception with no adverse side effects was 16 mg per kilogram of body weight, maximum - 1,500 mg. During the experiments, which approved sucralose, animals received various doses of the sweetener during different periods of time under a variety of methods of administration - oral and intravenous catheter. 

Experimental mice showed no sucralose side effects  side effects even at doses of 16,000 mg per kilogram of body weight in rats, similar results were obtained with 10 000 mg. This is equivalent to the consumption of 75-kg person 750 grams of sucralose per day. But amid the consumption of sucralose in an amount of 5% of the total amount of food the rats ate less, it is obvious, therefore, that such a huge amount of sweetener makes food tasteless. Loss of appetite, in turn, reduces the size cancer. Opponents of sucralose cause the data to support arguments about the effect of sucralose immune depending because gland produces T-immune cells. 

However, no decrease in appetite, or reduce cancer does not occur in humans. True, it did not stop some media from the warning against the consumption of sucralose, which supposedly weakens the immune system and causes cancer. Evidence to support such allegations had been given, but incorrect in this case, the results of experiments on animals. The human body produces nearly 85% of the consumed sucralose, absorbing only 15% of 'What is acquired is derived from the system within days. That is, sucralose is not retained in the body. She cannot get into the brain, cross the placenta in pregnant women, or get into breast milk. Doses of sucralose does not interact with other nutrients and do not contribute to the release of insulin. Studies have shown its absolute security for diabetics. 

Another accusation of sucralose based on the content of chlorine in it, contained in pesticides. But chlorine - is a natural element in the composition of such foods as lettuce, tomatoes, mushrooms, watermelon and peanut butter. Ordinary table salt - it is nothing like sodium chloride. 

Opponents of sucralose claim that since the beginning of the use of sucralose was not enough time to determine its impact on health. However, sucralose is consumed in Canada since 1991 - any side effects would have emerged long ago, but nothing like this is not observed. In addition, the doses used in the experiments on animals, was equivalent to the consumption of sweetened man for 13 years. 

The study, whose results were published a few years ago, compared the effects of consumption of artificial sweeteners including sucralose and sugar. The experiment lasted 10 weeks and was conducted over a group of people with obesity that have used or sugar or its substitutes. Participants in the experiment that consumed large amounts of sugar (28% of the total energy), showed an increase in energy, body weight, body weight and blood pressure, which was not observed among consumers of artificial sweeteners. 

Sucralose is an artificial sweetener which has zero calorie, does not cause insulin boost, six hundred times sweeter than sugar and twice sweeter than Saccharin. In the current era when people are obsessed by low-calorie foods, sucralose provide us with the promise of enjoying sugary foods without the fear of gaining weight. We all love ice creams, cakes, muffins, sodas, chocolate bars and lots of other sweet foods. Eliminating them from our diets so that we can keep our body in shape is not something to be fond of. When the chocolate manufacturers, soda manufacturers and bakers use sucralose in their products, it is like we are now allowed to fulfill our food cravings.

Every year, the use of sucralose in various food products increased by 10%, it has begun replacing the popularity of aspartame as sugar substitute. The FDA have stated that sucralose does not pose any carcinogenic, neurological or reproductive risks to human. However, there are reported cases of sucralose side effects. A safe daily intake for sucralose is 5 mg per Kilogram of our body weight, which means if you weigh 150 lbs or about 68 Kilogram, your limit of daily sucralose intake is 340 mg.

When our body ingest sucralose, it will not be recognized as food, which is actually the reason why it has no calories. Unfortunately, to make it unrecognizable by our body, sucralose requires multiple chemical processes. And since it is unrecognizable, despite just flushing it away from our system, our digestive system will even work harder to recognize the substance. This is especially true if we regularly consume this “unknown” substance. What happen next is that all those over-working digestive system and chemical exposure may give us health problems. Although cases are relatively rare, some of the commonly reported sucralose side effects are as follows:- Gastrointestinal upsets, such as diarrhea, bloating, cramp and nausea.

- Skin irritations, such as itching, hives, rashes and swelling.

- Mild headaches to intense migraines.

- Psychological problems, such as Agitation, anxiety and mood swings.

- Breathing difficulties, runny nose and cough.

- Consuming sucralose everyday may also cause tingling sensation in the lips, tongue and mouth.

Some researches also showed that very high doses of sucralose given to rodents shrank their thymus glands (up to 40% shrinkage), caused enlarged livers, damaged colons and caused kidney disorders. It is also been reported that sucralose reduced the amount of good bacteria in the intestines of rodents although this effect have not been reported in humans.